James’s behavior after Ginger bites him is a major departure from other men’s behavior after Ginger bit them—he seems to realize she’s biting out of fear, not meanness. And eventually, James and John’s kindness starts to show Ginger that she can trust them and relax. “Horse balls” were Victorian-era horse medicine; most formulations did nothing, but John implies that the most effective medicine a person can give a horse is kindness.